PDIA3 and GYPC

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		PDIA3	GYPC
Description		protein disulfide isomerase family A member 3	glycophorin C (Gerbich blood group)
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Disulfide Oxidoreductase Activity Peptide Disulfide Oxidoreductase Activity Identical Protein Binding	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Protein Folding Proteolysis Protein Phosphopantetheinylation Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Leukocyte Migration
Pathways		ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Cell surface interactions at the vascular wall
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Lead levels ( 26025379) Triglyceride levels ( 32203549)	Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)
Interacting Genes		21 interacting genes: APP BACE1 CALR CANX ERO1A ERP27 ESR1 GYPC HLA-A IFNG LGALS9 LINC01554 MDM2 MTNR1B PCAT1 SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A	13 interacting genes: ABHD16A AQP6 EPB41 GPR42 MPP1 PDIA3 PLPPR2 RHBDD1 SHISAL1 SLC10A6 TMEM14B TMEM88 TSPAN15
Entrez ID		2923	2995
HPRD ID		03625	00193
Ensembl ID		ENSG00000167004	ENSG00000136732
Uniprot IDs		P30101 V9HVY3	P04921
PDB IDs		2ALB 2DMM 2H8L 3F8U 6ENY	2EJY
Enriched GO Terms of Interacting Partners?
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