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ANKRD11 and BRCC3
Data Source:
BioGRID
(two hybrid)
ANKRD11
BRCC3
Description
ankyrin repeat domain 11
BRCA1/BRCA2-containing complex subunit 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Ubiquitin Ligase Complex
Nuclear Ubiquitin Ligase Complex
Spindle Pole
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
BRCA1-A Complex
BRISC Complex
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Metallopeptidase Activity
Enzyme Regulator Activity
Polyubiquitin Modification-dependent Protein Binding
Metal Ion Binding
Lys63-specific Deubiquitinase Activity
Isopeptidase Activity
Biological Process
Anatomical Structure Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Skeletal System Morphogenesis
Face Morphogenesis
Double-strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
Cell Cycle
Response To X-ray
Response To Ionizing Radiation
Protein Deubiquitination
Protein Phosphopantetheinylation
Positive Regulation Of DNA Repair
Regulation Of Catalytic Activity
Cell Division
Protein K63-linked Deubiquitination
Histone H2A K63-linked Deubiquitination
Signal Transduction Involved In G2 DNA Damage Checkpoint
Pathways
Metalloprotease DUBs
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Drugs
Zinc
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Eosinophil counts (
32888494
)
Hemoglobin levels (
32327693
)
Lymphocyte counts (
32888494
27863252
)
Monocyte count (
32888494
)
Venous thromboembolism (
31676865
)
Interacting Genes
93 interacting genes:
ABHD11
AGR2
ANKRD33
ARID3A
ARID5A
BHLHB9
BRCC3
C10orf82
C11orf1
C18orf54
C1QTNF2
CALCA
CCDC196
CCHCR1
CCN3
CDC23
CDCA7L
CDR2L
CEP44
COG4
DEPTOR
FAM136A
FAM221B
FOLR3
FTO
GOLGA2
GOLGA6L9
GRIPAP1
HAUS3
HDAC3
HDAC4
HDAC5
HOMEZ
HOOK2
HRAS
IGFBP6
IKZF1
ITGB3BP
KANK2
KPNA3
KPNA6
KRT34
LZTS2
MKRN3
MTFR1L
MTUS2
MXRA8
MYF5
NAB2
NCOA1
NCOA2
NCOA3
NOTO
NTAQ1
PDE4DIP
PIH1D2
PLAGL2
PPARA
RAC3
RCOR3
RINT1
RPH3AL
RSPO4
RUBCN
SERTAD3
SNRNP35
SPANXN2
SPATA2
SPRY1
SRC
STMN3
STRA8
SYTL3
TADA2B
TFIP11
TLE5
TNNI1
TRAF2
TRIM37
TRIM54
TSPOAP1
TTC23L
TXN
UFC1
USH1G
USP54
USP6
VDR
ZNF426
ZNF552
ZNF655
ZNF688
ZRANB1
11 interacting genes:
ANKRD11
BRCA1
FANCG
IFNAR1
NUMA1
SHMT2
SNAPC5
SUMO2
UBC
UBE2D1
UIMC1
Entrez ID
29123
79184
HPRD ID
12456
06465
Ensembl ID
ENSG00000167522
ENSG00000185515
Uniprot IDs
Q6UB99
P46736
PDB IDs
6H3C
6R8F
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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