DROSHA and ZNF512B

Data Source:
BioGRID (two hybrid)

		DROSHA	ZNF512B
Description		drosha ribonuclease III	zinc finger protein 512B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Postsynaptic Density Microprocessor Complex	Nucleoplasm
	Molecular Function	Lipopolysaccharide Binding RNA Binding Double-stranded RNA Binding Ribonuclease III Activity Protein Binding DEAD/H-box RNA Helicase Binding Protein Homodimerization Activity SMAD Binding Metal Ion Binding R-SMAD Binding Primary MiRNA Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	RNA Processing MiRNA Metabolic Process Positive Regulation Of Gene Expression RRNA Catabolic Process Production Of SiRNA Involved In RNA Interference Primary MiRNA Processing Pre-miRNA Processing Ribosome Biogenesis Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of MiRNA Metabolic Process
Pathways		MicroRNA (miRNA) biogenesis
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Lung function (FEV1) ( 26635082) Tuberculosis ( 30713548)	Birth weight ( 31043758) Mean platelet volume ( 32888494) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		4 interacting genes: DGCR8 SP1 TULP3 ZNF512B	71 interacting genes: AJUBA ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BANP BRD1 BTBD2 C11orf68 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 GOLGA2 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MDFI MEOX2 MTUS2 MYH10 NACC1 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RABEP1 RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2 ZNF143 ZYX
Entrez ID		29102	57473
HPRD ID		10196	13840
Ensembl ID		ENSG00000113360	ENSG00000196700
Uniprot IDs		Q9NRR4	Q96KM6
PDB IDs		2KHX 2NA2 5B16 6LXD 6LXE 6V5B 6V5C	2GQJ
Enriched GO Terms of Interacting Partners?
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