SSU72 and STAG2

Data Source:
BioGRID (enzymatic study)

		SSU72	STAG2
Description		SSU72 homolog, RNA polymerase II CTD phosphatase	stromal antigen 2
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GO Annotations	Cellular Component	Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Mitotic Spindle Pole
	Molecular Function	Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Chromatin Binding Protein Binding
	Biological Process	Termination Of RNA Polymerase II Transcription MRNA Polyadenylation Dephosphorylation Of RNA Polymerase II C-terminal Domain	Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle Mitotic Spindle Assembly
Pathways		RNA polymerase II transcribes snRNA genes	Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		4 interacting genes: MAPK8 MAPK9 RAD21 STAG2	7 interacting genes: ITGB1BP2 PLK1 PTEN RAD21 SSU72 STAG1 SUMO2
Entrez ID		29101	10735
HPRD ID		13712	05077
Ensembl ID		ENSG00000160075	ENSG00000101972
Uniprot IDs		Q9NP77	Q6AI02 Q6MZM3 Q6MZP3 Q8N3U4
PDB IDs		3O2Q 3O2S 4H3H 4H3K	4PJU 4PJW 4PK7 6QNX
Enriched GO Terms of Interacting Partners?
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