GRINA and FMO1

Data Source:
BioGRID (two hybrid)

		GRINA	FMO1
Description		glutamate ionotropic receptor NMDA type subunit associated protein 1	flavin containing dimethylaniline monoxygenase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ion Channel Binding	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Organic Acid Metabolic Process Xenobiotic Metabolic Process Response To Osmotic Stress Toxin Metabolic Process Drug Metabolic Process Response To Lipopolysaccharide NADPH Oxidation
Pathways			FMO oxidises nucleophiles
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422) LDL cholesterol ( 25961943) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010)	Metabolite levels ( 23823483) Sudden cardiac arrest ( 21658281) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		9 interacting genes: DRD2 FMO1 GGT6 GLP1R GPX8 KRTAP19-5 KRTAP6-2 TIAL1 TMEM242	6 interacting genes: CREB3 GRINA LEPROTL1 MFSD14B REEP4 SLC10A6
Entrez ID		2907	2326
HPRD ID		15927	00631
Ensembl ID		ENSG00000178719	ENSG00000010932
Uniprot IDs		Q7Z429	A0A024R934 B2RCG5 Q01740
PDB IDs
Enriched GO Terms of Interacting Partners?
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