FMO1 and MFSD14B

Data Source:
BioGRID (two hybrid)

		FMO1	MFSD14B
Description		flavin containing dimethylaniline monoxygenase 1	major facilitator superfamily domain containing 14B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Flavin Adenine Dinucleotide Binding NADP Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Organic Acid Metabolic Process Xenobiotic Metabolic Process Response To Osmotic Stress Toxin Metabolic Process Drug Metabolic Process Response To Lipopolysaccharide NADPH Oxidation	Transmembrane Transport
Pathways		FMO oxidises nucleophiles
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Sudden cardiac arrest ( 21658281) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		6 interacting genes: CREB3 GRINA LEPROTL1 MFSD14B REEP4 SLC10A6	75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		2326	84641
HPRD ID		00631	07869
Ensembl ID		ENSG00000010932	ENSG00000148110
Uniprot IDs		A0A024R934 B2RCG5 Q01740	Q5SR56
PDB IDs
Enriched GO Terms of Interacting Partners?
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