ZNF326 and GYS1

Data Source:
BioGRID (two hybrid)

		ZNF326	GYS1
Description		zinc finger protein 326	glycogen synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix Intracellular Membrane-bounded Organelle DBIRD Complex	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	RNA Polymerase II Complex Binding DNA Binding RNA Binding Protein Binding Metal Ion Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	MRNA Processing RNA Splicing Regulation Of DNA-templated Transcription, Elongation Regulation Of RNA Splicing	Glycogen Biosynthetic Process Heart Development
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Brain structure (hippocampal volume) ( 20197096) Major depressive disorder ( 27479909) Obsessive-compulsive symptoms ( 26859814) Thiopurine-induced digestive symptoms in inflammatory bowel disease ( 29923122)
Interacting Genes		8 interacting genes: GEMIN4 GYS1 KHDRBS3 KPNA5 NCOA5 PTEN SPTA1 VMAC	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		284695	2997
HPRD ID		15774	00721
Ensembl ID		ENSG00000162664	ENSG00000104812
Uniprot IDs		A0A0A0MRN4 Q5BKZ1	P13807
PDB IDs
Enriched GO Terms of Interacting Partners?
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