CXCL17 and CCL20

Data Source:
BioGRID (pull down)

		CXCL17	CCL20
Description		C-X-C motif chemokine ligand 17	C-C motif chemokine ligand 20
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Protein Binding Chemokine Activity CCR6 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Activation Of MAPK Activity Angiogenesis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of Monocyte Chemotaxis	Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Bacterium Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738 32296059) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Blood pressure ( 17903302) Crohn's disease ( 26192919) Eating disorders (purging via substances) ( 23568457) Inflammatory bowel disease ( 26192919) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 26192919)
Interacting Genes		16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2	11 interacting genes: CCL5 CCR6 CXCL11 CXCL12 CXCL17 CXCL5 MTDH PF4 TGFB3 VCAN XCL2
Entrez ID		284340	6364
HPRD ID		18264	03571
Ensembl ID		ENSG00000189377	ENSG00000115009
Uniprot IDs		Q6UXB2	P78556
PDB IDs			1M8A 2HCI 2JYO 5UR7 6WWZ
Enriched GO Terms of Interacting Partners?
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