SSC5D and MED21

Data Source:
BioGRID (two hybrid, two hybrid)

		SSC5D	MED21
Description		scavenger receptor cysteine rich family member with 5 domains	mediator complex subunit 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane Extracellular Matrix Collagen-containing Extracellular Matrix	Mediator Complex
	Molecular Function	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Endocytosis Defense Response Multicellular Organism Development Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Regulation Of Transcription By RNA Polymerase II RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Scavenging by Class B Receptors	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Height ( 28552196) Lung adenocarcinoma ( 28604730)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1	30 interacting genes: BLOC1S6 BORCS6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HGS HNF4A HTT MAGEA6 MAGEB4 MED29 MIEF1 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 TRIM72 VAV2 ZNF655 ZSCAN1
Entrez ID		284297	9412
HPRD ID		11444	09156
Ensembl ID		ENSG00000179954	ENSG00000152944
Uniprot IDs		A1L4H1	A0A024RAW0 Q13503
PDB IDs
Enriched GO Terms of Interacting Partners?
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