CRACR2B and IL36RN

Data Source:
BioGRID (two hybrid)

		CRACR2B	IL36RN
Description		calcium release activated channel regulator 2B	interleukin 36 receptor antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding
	Biological Process	Store-operated Calcium Entry Cellular Protein Localization Regulation Of Store-operated Calcium Entry	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways			Interleukin-36 pathway
Drugs
Diseases
GWAS		Body mass index ( 29273807)	Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)
Interacting Genes		15 interacting genes: APP CA13 CCDC187 DNAAF4 IDH1 IL36RN LNX1 PSMB3 RIN1 TCEANC TSGA10IP TSHZ2 TXN2 USP2 ZBTB25	18 interacting genes: AGR2 AP3M1 CNOT4 CRACR2B DDIT4L HPCA INCA1 IRAK4 MCM6 REL SH2B2 SKIL SSBP2 SSBP3 SSBP4 UBL4B ZKSCAN4 ZNF512B
Entrez ID		283229	26525
HPRD ID		14645	16112
Ensembl ID		ENSG00000177685	ENSG00000136695
Uniprot IDs		Q8N4Y2	A0A024R518 Q9UBH0
PDB IDs			4P0J 4P0K 4P0L
Enriched GO Terms of Interacting Partners?
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