GP9 and GP1BB

Data Source:
HPRD (in vivo)

		GP9	GP1BB
Description		glycoprotein IX platelet	glycoprotein Ib platelet subunit beta
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation	Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation
Pathways		Intrinsic Pathway of Fibrin Clot Formation GP1b-IX-V activation signalling Platelet Adhesion to exposed collagen Platelet Aggregation (Plug Formation) Defective F9 activation	Intrinsic Pathway of Fibrin Clot Formation GP1b-IX-V activation signalling Platelet Adhesion to exposed collagen Platelet Aggregation (Plug Formation) Defective F9 activation
Drugs		Quinine
Diseases		Bernard-Soulier syndrome; Giant platelet syndrome	Bernard-Soulier syndrome; Giant platelet syndrome
GWAS		Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	DNA methylation (parent-of-origin) ( 23725790) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252)
Interacting Genes		5 interacting genes: APPBP2 GP1BA GP1BB HOXA1 SPRY2	4 interacting genes: GP9 PRKACA TGFB1I1 YWHAZ
Entrez ID		2815	2812
HPRD ID		01432	00729
Ensembl ID		ENSG00000169704	ENSG00000203618
Uniprot IDs		P14770	P13224
PDB IDs		3REZ	3REZ 3RFE
Enriched GO Terms of Interacting Partners?
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