GP1BB and TGFB1I1

Data Source:
BioGRID (pull down, affinity chromatography technology)

		GP1BB	TGFB1I1
Description		glycoprotein Ib platelet subunit beta	transforming growth factor beta 1 induced transcript 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation	Cell Adhesion Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		Intrinsic Pathway of Fibrin Clot Formation GP1b-IX-V activation signalling Platelet Adhesion to exposed collagen Platelet Aggregation (Plug Formation) Defective F9 activation
Drugs
Diseases		Bernard-Soulier syndrome; Giant platelet syndrome
GWAS		DNA methylation (parent-of-origin) ( 23725790) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252)	Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: GP9 PRKACA TGFB1I1 YWHAZ	29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL
Entrez ID		2812	7041
HPRD ID		00729	03831
Ensembl ID		ENSG00000203618	ENSG00000140682
Uniprot IDs		P13224	A0A024QZE7 O43294
PDB IDs		3REZ 3RFE
Enriched GO Terms of Interacting Partners?
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