AMT and F2RL2

Data Source:
BioGRID (two hybrid)

		AMT	F2RL2
Description		aminomethyltransferase	coagulation factor II thrombin receptor like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Protein-containing Complex
	Molecular Function	Aminomethyltransferase Activity Transaminase Activity	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity
	Biological Process	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System	G Protein-coupled Receptor Signaling Pathway Blood Coagulation Response To Wounding Platelet Activation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Thrombin-activated Receptor Signaling Pathway
Pathways		Glycine degradation	Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)
Drugs		Tetrahydrofolic acid NADH 5-methyltetrahydrofolic acid
Diseases		Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptom (depressed mood) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)
Interacting Genes		2 interacting genes: PDLIM4 VAC14	8 interacting genes: CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3
Entrez ID		275	2151
HPRD ID		01997	03561
Ensembl ID		ENSG00000145020	ENSG00000164220
Uniprot IDs		A0A024R2U7 P48728	O00254
PDB IDs		1WSR 1WSV
Enriched GO Terms of Interacting Partners?
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