PCLO and PCAT1

Data Source:
BioGRID (unspecified method)

		PCLO	PCAT1
Description		piccolo presynaptic cytomatrix protein	prostate cancer associated transcript 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Postsynaptic Density Axon Synapse Cytoskeleton Of Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Calcium Ion Binding Profilin Binding Calcium-dependent Phospholipid Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	Cytoskeleton Organization Synaptic Vesicle Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Protein Localization To Synapse Maintenance Of Presynaptic Active Zone Structure Synaptic Vesicle Clustering Presynapse To Nucleus Signaling Pathway Presynaptic Active Zone Assembly
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Energy expenditure (24h) ( 28476931) Grapefruit juice consumption ( 31046077) Major depressive disorder ( 21621269 28540843 20351715) Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)	Body mass index ( 25673413) Heel bone mineral density ( 30598549 28869591) Intracranial aneurysm ( 29531279) Lung cancer in never smokers ( 28604730)
Interacting Genes		4 interacting genes: ERC2 GIT1 GIT2 PCAT1	12 interacting genes: AAMP CASD1 FAF2 GJA10 GRWD1 HNRNPH1 NAV3 PCCB PCLO PDIA3 RPL11 TUFM
Entrez ID		27445	100750225
HPRD ID		16078
Ensembl ID		ENSG00000186472	ENSG00000253438
Uniprot IDs		Q9Y6V0
PDB IDs		1UJD
Enriched GO Terms of Interacting Partners?
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