STK36 and CLNK

Data Source:
BioGRID (two hybrid)

		STK36	CLNK
Description		serine/threonine kinase 36	cytokine dependent hematopoietic cell linker
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol	Cytoplasm Protein-containing Complex Mast Cell Granule
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Protein-containing Complex Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Protein Phosphorylation Smoothened Signaling Pathway Positive Regulation Of Hh Target Transcription Factor Activity Brain Development Post-embryonic Development Positive Regulation Of Smoothened Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Cilium Assembly	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Amyotrophic lateral sclerosis ( 22959728) Hematocrit ( 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Male-pattern baldness ( 28196072) Red blood cell count ( 32888494) Refractive error ( 32231278)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		10 interacting genes: CDK5RAP2 CDK9 CLNK FRMPD4 GLI1 GLI2 GLI3 MAST2 MID1 SUFU	29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		27148	116449
HPRD ID		09631	14720
Ensembl ID		ENSG00000163482	ENSG00000109684
Uniprot IDs		A0A140VJW1 Q9NRP7	Q7Z7G1
PDB IDs
Enriched GO Terms of Interacting Partners?
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