PELP1 and BLOC1S1

Data Source:
BioGRID (two hybrid)

		PELP1	BLOC1S1
Description		proline, glutamate and leucine rich protein 1	biogenesis of lysosomal organelles complex 1 subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Transcriptionally Active Chromatin MLL1 Complex	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Transcription Factor Binding	Protein Binding
	Biological Process	RRNA Processing Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estrogen Stimulus	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Eosinophil counts ( 29403010)	Refractive error ( 32231278)
Interacting Genes		25 interacting genes: AR BAG6 BCAS3 BLOC1S1 CREBBP EP300 ESR1 ESR2 H1-1 H2AC20 H2BC21 H3-3A H4C1 HGS NFKB1 NR3C1 PTEN RB1 SMAD9 SNCA SRC STAT3 SUMO2 TOM1L1 TP53	18 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 DCTN2 FBXO44 HGS MAGEB4 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPC5 SNAPIN USHBP1
Entrez ID		27043	2647
HPRD ID		10144	03263
Ensembl ID		ENSG00000141456	ENSG00000135441
Uniprot IDs		B4DEX7 B4DR36 C9JFV4 E7EV54 Q8IZL8	P78537
PDB IDs
Enriched GO Terms of Interacting Partners?
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