ATP2C1 and GGCX

Data Source:
HPRD (in vivo)

		ATP2C1	GGCX
Description		ATPase secretory pathway Ca2+ transporting 1	gamma-glutamyl carboxylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Calcium Transmembrane Transporter Activity, Phosphorylative Mechanism ATP Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Manganese Transmembrane Transporter Activity, Phosphorylative Mechanism ATPase Activity Metal Ion Binding	Gamma-glutamyl Carboxylase Activity Vitamin Binding
	Biological Process	Calcium Ion Transport Manganese Ion Transport Cellular Calcium Ion Homeostasis Epidermis Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Actin Cytoskeleton Reorganization Golgi Calcium Ion Homeostasis Golgi Calcium Ion Transport Ion Transmembrane Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Calcium Ion Transmembrane Transport Manganese Ion Transmembrane Transport Proton Transmembrane Transport	Cellular Protein Modification Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation
Pathways		Ion transport by P-type ATPases	Gamma-carboxylation of protein precursors Gamma-carboxylation of protein precursors Defective gamma-carboxylation of F9
Drugs		Enflurane Isoflurane Methoxyflurane Desflurane Sevoflurane Calcium	Coagulation factor VIIa Recombinant Human Coagulation Factor IX (Recombinant) Glutamic acid Menadione Phylloquinone Anisindione Kappadione Coagulation Factor IX Human
Diseases		Hailey-Hailey disease; Benign familial pemphigus	Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency Combined deficiency of vitamin K-dependent clotting factors (VKCFD)
GWAS		Refractive error ( 32231278) Restless legs syndrome ( 29029846) Waist circumference ( 28552196)	Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) High light scatter reticulocyte count ( 32888494) Myocardial infarction ( 26343387) Prostate cancer ( 21743467) Triglyceride levels ( 32203549)
Interacting Genes		3 interacting genes: F2RL1 GPR35 GTF2IRD1	7 interacting genes: BGLAP F10 F2 F7 F9 PROC SRPK2
Entrez ID		27032	2677
HPRD ID		05089	00665
Ensembl ID		ENSG00000017260	ENSG00000115486
Uniprot IDs		B4E295 B4E2Q0 P98194	P38435
PDB IDs
Enriched GO Terms of Interacting Partners?
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