MDGA1 and NLGN2

Data Source:
BioGRID (pull down)

		MDGA1	NLGN2
Description		MAM domain containing glycosylphosphatidylinositol anchor 1	neuroligin 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Anchored Component Of Plasma Membrane GABA-ergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Inhibitory Synapse Spanning Component Of Membrane Glycinergic Synapse Dopaminergic Synapse Symmetric, GABA-ergic, Inhibitory Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Molecular_function	Signaling Receptor Activity Neurexin Family Protein Binding Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Neuron Migration Brain Development Spinal Cord Association Neuron Differentiation Regulation Of Synaptic Membrane Adhesion Regulation Of Presynapse Assembly	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Sensory Perception Of Pain Positive Regulation Of Insulin Secretion Positive Regulation Of Synaptic Transmission, GABAergic Protein Localization To Synapse Locomotory Exploration Behavior Cell-cell Junction Maintenance Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Terminal Button Organization Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Gephyrin Clustering Involved In Postsynaptic Density Assembly Postsynaptic Density Protein 95 Clustering Positive Regulation Of Inhibitory Postsynaptic Potential Cell-cell Adhesion Presynapse Assembly Positive Regulation Of Protein Localization To Synapse Inhibitory Synapse Assembly Regulation Of AMPA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Clustering
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 27171184) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Lamb consumption ( 32066663) Neurological blood protein biomarker levels ( 31320639) Restless legs syndrome ( 29029846)	Refractive error ( 32231278) Uterine fibroids ( 30194396)
Interacting Genes		2 interacting genes: LNX2 NLGN2	8 interacting genes: DLG2 DLG3 DLG4 MDGA1 NRXN1 NRXN2 NRXN3 PATJ
Entrez ID		266727	57555
HPRD ID		14374	07348
Ensembl ID		ENSG00000112139	ENSG00000169992
Uniprot IDs		Q8NFP4	Q8NFZ4
PDB IDs		5V5V 5V5W 5XEQ	5XEQ
Enriched GO Terms of Interacting Partners?
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