SSBP2 and IL36RN

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SSBP2	IL36RN
Description		single stranded DNA binding protein 2	interleukin 36 receptor antagonist
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Single-stranded DNA Binding	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways			Interleukin-36 pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 21079607) Bipolar disorder ( 31043756) Glioblastoma ( 22472174) Plateletcrit ( 32888494)	Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)
Interacting Genes		7 interacting genes: CDK6 EWSR1 IL36RN LDB1 LDB2 PIN1 TOM1	18 interacting genes: AGR2 AP3M1 CNOT4 CRACR2B DDIT4L HPCA INCA1 IRAK4 MCM6 REL SH2B2 SKIL SSBP2 SSBP3 SSBP4 UBL4B ZKSCAN4 ZNF512B
Entrez ID		23635	26525
HPRD ID		09577	16112
Ensembl ID		ENSG00000145687	ENSG00000136695
Uniprot IDs		A0A087X159 P81877	A0A024R518 Q9UBH0
PDB IDs		6IWV 6TYD	4P0J 4P0K 4P0L
Enriched GO Terms of Interacting Partners?
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