GCGR and TGM2

Data Source:
BioGRID (two hybrid)

		GCGR	TGM2
Description		glucagon receptor	transglutaminase 2
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Focal Adhesion Intrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Glucagon Receptor Activity Guanyl-nucleotide Exchange Factor Activity G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding GTP Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Response To Nutrient Regulation Of Blood Pressure Cellular Response To Starvation Positive Regulation Of Gene Expression Glucose Homeostasis Response To Starvation Regulation Of Catalytic Activity Regulation Of Glycogen Metabolic Process Cellular Response To Glucagon Stimulus	Blood Vessel Remodeling Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Phosphopantetheinylation Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apoptotic Cell Clearance Positive Regulation Of Cell Adhesion Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Inflammatory Response Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Branching Involved In Salivary Gland Morphogenesis Salivary Gland Cavitation
Pathways
Drugs		Glucagon	Guanosine-5'-Diphosphate Hexylresorcinol
Diseases
GWAS		Hematocrit ( 32888494)
Interacting Genes		4 interacting genes: GCG GNAS TGM2 TP63	59 interacting genes: A2M ABCA1 ACTB ADAR ALDOA ANKRD28 ANXA1 APP ARNT ATF4 BNIP3 C3 CASP3 CBL CERT1 CSNK2A2 EIF5A FN1 FNTA GCGR GRN GSTP1 H2BC21 H2BC8 HNRNPF HNRNPUL1 HP HSPA1A HSPA1B HSPA8 HTT ITGB1 ITGB3 KPNA3 KPNA4 LACRT LTBP1 MAP3K12 PAK1 PINK1 PLCD1 PPHLN1 PXN RB1 RELA RHOA S100A7 SERPINF2 SERTAD1 SIPA1L2 SLC7A9 SMAD2 SMAD3 SPARC TAB2 TMEM176A TMSB4X TUBB ZNF512B
Entrez ID		2642	7052
HPRD ID		00678	01825
Ensembl ID		ENSG00000215644	ENSG00000198959
Uniprot IDs		P47871	B4DIT7 B4DTN7 P21980 V9HWG3
PDB IDs		2A83 3CZF 4ERS 4L6R 4LF3 5EE7 5XEZ 6LMK 6LML 6WHC 6WPW	1FAU 1KV3 2Q3Z 3LY6 3S3J 3S3P 3S3S 4PYG 6A8P
Enriched GO Terms of Interacting Partners?
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