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TGM2 and CERT1
Data Source:
BioGRID
(two hybrid)
TGM2
CERT1
Description
transglutaminase 2
ceramide transporter 1
Image
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Focal Adhesion
Intrinsic Component Of Plasma Membrane
Collagen-containing Extracellular Matrix
Extracellular Exosome
Nucleoplasm
Mitochondrion
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein-glutamine Gamma-glutamyltransferase Activity
Protein Binding
GTP Binding
Protein Domain Specific Binding
Identical Protein Binding
Metal Ion Binding
Protein Binding
Kinase Activity
Phosphatidylinositol-4-phosphate Binding
Ceramide Binding
Ceramide Transfer Activity
Ceramide 1-phosphate Binding
Ceramide 1-phosphate Transfer Activity
Biological Process
Blood Vessel Remodeling
Peptide Cross-linking
Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine
Protein Phosphopantetheinylation
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Positive Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Apoptotic Cell Clearance
Positive Regulation Of Cell Adhesion
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Inflammatory Response
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Branching Involved In Salivary Gland Morphogenesis
Salivary Gland Cavitation
Cell Morphogenesis
In Utero Embryonic Development
Heart Morphogenesis
Ceramide Metabolic Process
Muscle Contraction
Immune Response
Endoplasmic Reticulum Organization
Signal Transduction
Cell Population Proliferation
Phosphorylation
Sphingolipid Biosynthetic Process
Response To Endoplasmic Reticulum Stress
ER To Golgi Ceramide Transport
Ceramide Transport
Lipid Homeostasis
Mitochondrion Morphogenesis
Intermembrane Lipid Transfer
Intermembrane Sphingolipid Transfer
Ceramide 1-phosphate Transport
Pathways
Drugs
Guanosine-5'-Diphosphate
Hexylresorcinol
Diseases
GWAS
Interacting Genes
59 interacting genes:
A2M
ABCA1
ACTB
ADAR
ALDOA
ANKRD28
ANXA1
APP
ARNT
ATF4
BNIP3
C3
CASP3
CBL
CERT1
CSNK2A2
EIF5A
FN1
FNTA
GCGR
GRN
GSTP1
H2BC21
H2BC8
HNRNPF
HNRNPUL1
HP
HSPA1A
HSPA1B
HSPA8
HTT
ITGB1
ITGB3
KPNA3
KPNA4
LACRT
LTBP1
MAP3K12
PAK1
PINK1
PLCD1
PPHLN1
PXN
RB1
RELA
RHOA
S100A7
SERPINF2
SERTAD1
SIPA1L2
SLC7A9
SMAD2
SMAD3
SPARC
TAB2
TMEM176A
TMSB4X
TUBB
ZNF512B
18 interacting genes:
ACTL8
AQP2
ARL6IP1
BSND
CBS
COL4A3
CSNK1G2
FTSJ1
ITGB3BP
MINAR1
PM20D2
POM121
REEP6
RTN3
RTN4
SMU1
STX2
TGM2
Entrez ID
7052
10087
HPRD ID
01825
05246
Ensembl ID
ENSG00000198959
ENSG00000113163
Uniprot IDs
B4DIT7
B4DTN7
P21980
V9HWG3
A0A024RAJ5
A0A2R8Y7C5
Q9Y5P4
PDB IDs
1FAU
1KV3
2Q3Z
3LY6
3S3J
3S3P
3S3S
4PYG
6A8P
2E3M
2E3N
2E3O
2E3P
2E3Q
2E3R
2E3S
2RSG
2Z9Y
2Z9Z
3H3Q
3H3R
3H3S
3H3T
4HHV
5JJD
5ZYG
5ZYH
5ZYI
5ZYJ
5ZYK
5ZYL
5ZYM
6IEZ
6IF0
6J0O
6J81
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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