FBXO3 and CRYBA1

Data Source:
BioGRID (genetic interference)

		FBXO3	CRYBA1
Description		F-box protein 3	crystallin beta A1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Proteolysis Protein Ubiquitination	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Coronary artery calcification ( 23870195) Fruit consumption ( 32066663) Morning person ( 30696823)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: SKP1 SMURF1	24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3
Entrez ID		26273	1411
HPRD ID		16433	00429
Ensembl ID		ENSG00000110429	ENSG00000108255
Uniprot IDs		Q49AF1 Q9UK99	P05813
PDB IDs		5HDW
Enriched GO Terms of Interacting Partners?
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