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FBXO4 and ELF4
Data Source:
HPRD
(in vivo)
FBXO4
ELF4
Description
F-box protein 4
E74 like ETS transcription factor 4
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Cytoplasm
Cytosol
SCF Ubiquitin Ligase Complex
Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PML Body
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Protein Polyubiquitination
Aging
Posttranscriptional Regulation Of Gene Expression
Protein Ubiquitination
Cellular Homeostasis
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Stability
Protein Destabilization
Positive Regulation Of Telomere Maintenance Via Telomerase
Common Myeloid Progenitor Cell Proliferation
Post-translational Protein Modification
Negative Regulation Of Fibroblast Proliferation
Cellular Response To Ionizing Radiation
Negative Regulation Of Protein Localization To Nucleus
Positive Regulation Of Protein Polyubiquitination
Regulation Of DNA Damage Checkpoint
Natural Killer Cell Proliferation
NK T Cell Proliferation
Regulation Of Transcription By RNA Polymerase II
Cell Differentiation
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Interacting Genes
8 interacting genes:
CCND1
CDC34
ELF4
FXR1
SKP1
TERF1
TNNI3K
UBE2D2
9 interacting genes:
CASP4
FBXO4
FBXO7
NPM1
PML
RUNX1
SET
SKP2
UBB
Entrez ID
26272
2000
HPRD ID
09949
06499
Ensembl ID
ENSG00000151876
ENSG00000102034
Uniprot IDs
B3KNA0
D6RAJ6
Q9UKT5
Q99607
PDB IDs
3L2O
3L82
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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