WIPI2 and MRRF

Data Source:
BioGRID (two hybrid)

		WIPI2	MRRF
Description		WD repeat domain, phosphoinositide interacting 2	mitochondrial ribosome recycling factor
Image		No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Nucleoplasm Autophagosome Cytosol Membrane Extrinsic Component Of Membrane Protein-containing Complex Phagophore Assembly Site Membrane	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding Ribosomal Large Subunit Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Cellular Response To Starvation Macroautophagy Protein Localization To Phagophore Assembly Site Autophagy Of Nucleus Protein Lipidation Involved In Autophagosome Assembly Autophagosome Maturation Xenophagy	Translation Ribosome Disassembly Mitochondrial Translational Termination
Pathways		Macroautophagy	Mitochondrial translation termination
Drugs
Diseases
GWAS		Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494)
Interacting Genes		16 interacting genes: ARL6IP1 COPS6 DDB1 DGAT2L6 FKBP7 MRRF MTOR OPTN POT1 RABAC1 REEP6 RPTOR STRN4 SYP TERF2IP UBE2L3	10 interacting genes: AGTRAP APP BANP CMTM5 FAM9B FHL3 KRT40 SYP WIPI2 ZNF408
Entrez ID		26100	92399
HPRD ID		15679	06856
Ensembl ID		ENSG00000157954	ENSG00000148187
Uniprot IDs		A0A024R823 Q9Y4P8	Q96E11
PDB IDs			6NU2 6ZS9
Enriched GO Terms of Interacting Partners?
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