WIPI2 and DGAT2L6

Data Source:
BioGRID (two hybrid)

		WIPI2	DGAT2L6
Description		WD repeat domain, phosphoinositide interacting 2	diacylglycerol O-acyltransferase 2 like 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Nucleoplasm Autophagosome Cytosol Membrane Extrinsic Component Of Membrane Protein-containing Complex Phagophore Assembly Site Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding O-acyltransferase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Cellular Response To Starvation Macroautophagy Protein Localization To Phagophore Assembly Site Autophagy Of Nucleus Protein Lipidation Involved In Autophagosome Assembly Autophagosome Maturation Xenophagy	Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Acylglycerol Acyl-chain Remodeling
Pathways		Macroautophagy	Acyl chain remodeling of DAG and TAG
Drugs
Diseases
GWAS		Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494)
Interacting Genes		16 interacting genes: ARL6IP1 COPS6 DDB1 DGAT2L6 FKBP7 MRRF MTOR OPTN POT1 RABAC1 REEP6 RPTOR STRN4 SYP TERF2IP UBE2L3	45 interacting genes: ABHD4 ABHD5 ACSF2 AQP6 ARFIP2 BNIP2 CIAO2A DIABLO ECPAS FARS2 FBXL19 FCER1G GAD2 GPR152 HSD17B11 MCEMP1 MPP1 MTERF4 MYG1 NAPB NDRG4 PBX3 PGRMC2 PITPNC1 REEP4 RNF144A RNF5 RUSF1 SCAND1 SCN3B SLC10A1 SLC10A6 SMG9 SNX4 STAR THAP4 TMED8 TMEM143 TMEM14B TMEM255B TMEM31 TMX2 TTPA TUFM WIPI2
Entrez ID		26100	347516
HPRD ID		15679	13141
Ensembl ID		ENSG00000157954	ENSG00000184210
Uniprot IDs		A0A024R823 Q9Y4P8	Q6ZPD8
PDB IDs
Enriched GO Terms of Interacting Partners?
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