HERC4 and HERC6

		HERC4	HERC6
Description		HECT and RLD domain containing E3 ubiquitin protein ligase 4	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Cytosol	Nucleoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity	Ubiquitin-protein Transferase Activity
	Biological Process	Spermatogenesis Protein Ubiquitination Cell Differentiation Negative Regulation Of Smoothened Signaling Pathway	Protein Polyubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 28892062)	Lean body mass ( 28552196) Metabolite levels ( 22916037) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: HERC6 UBC UBE2D2 UBE2E3 UBE2J2 UBE2L3	4 interacting genes: HERC3 HERC4 NME2 UBE2L3
Entrez ID		26091	55008
HPRD ID		13646	13647
Ensembl ID		ENSG00000148634	ENSG00000138642
Uniprot IDs		A0A024QZN8 Q5GLZ8	Q8IVU3
PDB IDs			5W87
Enriched GO Terms of Interacting Partners?
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