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POLDIP2 and MAD2L2
Data Source:
BioGRID
(two hybrid)
POLDIP2
MAD2L2
Description
DNA polymerase delta interacting protein 2
mitotic arrest deficient 2 like 2
Image
GO Annotations
Cellular Component
Nucleus
Mitochondrion
Mitochondrial Matrix
Mitochondrial Nucleoid
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Chromosome
Nucleolus
Spindle
Cytosol
Zeta DNA Polymerase Complex
Site Of Double-strand Break
Molecular Function
DNA Binding
Protein Binding
RNA Polymerase II Activating Transcription Factor Binding
Protein Binding
JUN Kinase Binding
Biological Process
Negative Regulation Of Macroautophagy
Positive Regulation Of Mitotic Cell Cycle
Mitochondrion Morphogenesis
Error-free Translesion Synthesis
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Double-strand Break Repair
Actin Filament Organization
Mitotic Spindle Assembly Checkpoint
Negative Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Transcription By Competitive Promoter Binding
Positive Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Protein Catabolic Process
Error-prone Translesion Synthesis
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Isotype Switching
Positive Regulation Of Transcription, DNA-templated
Cell Division
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Ubiquitin Protein Ligase Activity
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Negative Regulation Of Transcription Regulatory Region DNA Binding
Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
Osteoprotegerin levels (
25080503
)
Arterial stiffness (brachial-femoral pulse wave velocity) (
32790701
)
Visceral adipose tissue adjusted for BMI (
22589738
)
Interacting Genes
19 interacting genes:
AGTRAP
ALAS1
APP
ASCC2
CHCHD2
CPE
DNAAF6
FBXO7
HDAC6
MAD2L2
MTUS2
PCNA
PDPK1
POLD2
POLN
PTEN
REV1
SELENBP1
TAB1
47 interacting genes:
ADAM15
ADAM17
ADAM9
C20orf85
CAMK2B
CDC20
CDH1
DEPDC5
ELK1
FAM217B
FTO
FZR1
GSC2
IKZF1
IKZF3
INCA1
KCTD9
KRT34
MAD2L1
MAD2L1BP
MBD3L1
MYBPC2
PLAGL2
POLDIP2
PPM1B
PRCC
PRR5L
PRRC2A
RAB11FIP4
RBBP6
REL
REV1
REV3L
SFI1
SHLD1
TCF4
THAP6
TRIM27
TRIM54
TRIM7
YPEL3
YY1AP1
ZBED1
ZMYND12
ZNF511
ZNF558
ZNF655
Entrez ID
26073
10459
HPRD ID
17874
07246
Ensembl ID
ENSG00000004142
ENSG00000116670
Uniprot IDs
B4DEM9
Q9Y2S7
A0A024R4I4
Q9UI95
PDB IDs
6Z9C
3ABD
3ABE
3VU7
4EXT
4GK0
4GK5
5XPT
5XPU
6BC8
6BCD
6BI7
6K07
6K08
6KEA
6KTO
6NIF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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