RAB11FIP5 and MOGS

Data Source:
BioGRID (two hybrid)

		RAB11FIP5	MOGS
Description		RAB11 family interacting protein 5	mannosyl-oligosaccharide glucosidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Mitochondrial Outer Membrane Early Endosome Golgi Apparatus Secretory Granule Transport Vesicle Membrane Early Endosome Membrane Centriolar Satellite Intracellular Membrane-bounded Organelle Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Gamma-tubulin Binding	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity
	Biological Process	Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Exocytosis Negative Regulation Of Adiponectin Secretion Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process
Pathways			Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Non-word reading ( 30741946) Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype) ( 29240982) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		9 interacting genes: ARF6 NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 RO60 YWHAG	1 interacting genes: CHGB
Entrez ID		26056	7841
HPRD ID		16117	03214
Ensembl ID		ENSG00000135631	ENSG00000115275
Uniprot IDs		Q9BXF6 Q9UFM0	A0A384MDR6 Q13724 Q58F09
PDB IDs
Enriched GO Terms of Interacting Partners?
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