RAB11FIP5 and RAB14

Data Source:
BioGRID (two hybrid)

		RAB11FIP5	RAB14
Description		RAB11 family interacting protein 5	RAB14, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Mitochondrial Outer Membrane Early Endosome Golgi Apparatus Secretory Granule Transport Vesicle Membrane Early Endosome Membrane Centriolar Satellite Intracellular Membrane-bounded Organelle Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane	Golgi Membrane Lysosome Lysosomal Membrane Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Stack Trans-Golgi Network Cytosol Plasma Membrane Cilium Endomembrane System Trans-Golgi Network Transport Vesicle Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding Gamma-tubulin Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Exocytosis Negative Regulation Of Adiponectin Secretion Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Defense Response To Bacterium Neutrophil Degranulation Regulation Of Embryonic Development Intracellular Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Non-word reading ( 30741946) Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype) ( 29240982) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)	Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Interacting Genes		9 interacting genes: ARF6 NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 RO60 YWHAG	12 interacting genes: ADRB2 APP CHM EXOC5 FAM71C OCRL OPTN RAB11FIP5 RBSN RUFY1 SH3BP5L SMURF2
Entrez ID		26056	51552
HPRD ID		16117	06693
Ensembl ID		ENSG00000135631	ENSG00000119396
Uniprot IDs		Q9BXF6 Q9UFM0	A0A024R845 P61106
PDB IDs			1Z0F 4D0G 4DRZ
Enriched GO Terms of Interacting Partners?
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