L3MBTL1 and SLC12A5

Data Source:
BioGRID (proximity labelling technology)

		L3MBTL1	SLC12A5
Description		L3MBTL histone methyl-lysine binding protein 1	solute carrier family 12 member 5
Image
GO Annotations	Cellular Component	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Synapse Cell Periphery
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding	Chloride Transmembrane Transporter Activity Potassium:chloride Symporter Activity
	Biological Process	Chromatin Organization Regulation Of Mitotic Nuclear Division Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator	Ion Transport Cellular Ion Homeostasis Cell Volume Homeostasis Hypotonic Response Chemical Synaptic Transmission Learning Cellular Chloride Ion Homeostasis Multicellular Organism Growth Thermosensory Behavior Response To Drug Chloride Ion Homeostasis Potassium Ion Homeostasis Dendritic Spine Development Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Regulation of TP53 Activity through Methylation	Cation-coupled Chloride cotransporters
Drugs		2-(N-morpholino)ethanesulfonic acid	Potassium chloride Bumetanide
Diseases
GWAS		Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)	Chronotype ( 30696823) Crohn's disease ( 28067908) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Systemic sclerosis ( 29293537) Triglyceride levels ( 32154731)
Interacting Genes		7 interacting genes: CBX3 ETV6 ETV7 H1-5 H4-16 RB1 SETD7	2 interacting genes: CCR4 F2RL1
Entrez ID		26013	57468
HPRD ID		16387	09469
Ensembl ID		ENSG00000185513	ENSG00000124140
Uniprot IDs		Q9Y468	Q9H2X9
PDB IDs		1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN 6BYB	6M23
Enriched GO Terms of Interacting Partners?
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