TENM4 and LCE3D

Data Source:
BioGRID (two hybrid)

		TENM4	LCE3D
Description		teneurin transmembrane protein 4	late cornified envelope 3D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Cytosol
	Molecular Function	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding	Protein Binding
	Biological Process	Gastrulation With Mouth Forming Second Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Myelination Positive Regulation Of Myelination Central Nervous System Myelin Formation Neuron Development Positive Regulation Of Oligodendrocyte Differentiation Cardiac Muscle Cell Proliferation Cardiac Cell Fate Specification Positive Regulation Of Gastrulation	Cornification
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hair greying ( 26926045) Lactate dehydrogenase levels ( 29403010) Lung cancer in never smokers ( 28604730) Night sleep phenotypes ( 27126917) Right lateral prefrontal cortical growth ( 29682794) Tourette syndrome ( 30818990)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Psoriasis ( 25854761 20953190 23143594 19169255)
Interacting Genes		8 interacting genes: DOCK2 HOXB9 LCE3D LGALS4 PLSCR4 SHFL ZNF587 ZNF696	55 interacting genes: ADAMTSL4 ALPP CCN3 CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-5 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2B LCE2C MDFI NBPF19 NOTCH2NLA PCSK5 RGS17 RGS20 SDC3 SPRY1 SPRY3 SRPK1 SRPK2 TENM4 TGFB1 TRIM42 TSPAN4 VWC2
Entrez ID		26011	84648
HPRD ID		19400	17263
Ensembl ID		ENSG00000149256	ENSG00000163202
Uniprot IDs		Q6N022	Q9BYE3
PDB IDs
Enriched GO Terms of Interacting Partners?
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