RPL36 and ARHGAP45

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		RPL36	ARHGAP45
Description		ribosomal protein L36	Rho GTPase activating protein 45
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome	Extracellular Region Cytosol Membrane Ruffle Membrane Secretory Granule Lumen Azurophil Granule Lumen
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Intracellular Signal Transduction Neutrophil Degranulation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: APP DUX4 PTEN RPL18A	9 interacting genes: BICD2 GMIP GOLGA2 HSF2BP PIBF1 PPP1R13B RINT1 TRIM50 ZUP1
Entrez ID		25873	23526
HPRD ID		10201	03097
Ensembl ID		ENSG00000130255	ENSG00000180448
Uniprot IDs		Q9Y3U8	B3KVA9 B3KXW7 F5H1R4 K7ES92 K7ES98 Q8IYN3 Q92619
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	3D25 3FT3
Enriched GO Terms of Interacting Partners?
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