RHBDD3 and WBP2

Data Source:
BioGRID (two hybrid)

		RHBDD3	WBP2
Description		rhomboid domain containing 3	WW domain binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Chromatin Nucleus Cytoplasm
	Molecular Function	Serine-type Endopeptidase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding
	Biological Process	MAPK Cascade Liver Development Regulation Of Acute Inflammatory Response Proteolysis Response To Xenobiotic Stimulus Negative Regulation Of Natural Killer Cell Activation Positive Regulation Of Protein Catabolic Process Regulation Of Protein Secretion	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Pancreatic cancer ( 25086665)	Adult body size ( 32376654) Platelet count ( 32888494) Red blood cell count ( 32888494) White matter hyperintensities ( 32358547)
Interacting Genes		1 interacting genes: WBP2	54 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 BAG3 CCT7 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HOMER3 HUWE1 ITCH KRT18 KRT8 KRT9 LGALS8 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 SMAD5 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE2D3 UBE2E3 UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1
Entrez ID		25807	23558
HPRD ID		12800	06097
Ensembl ID		ENSG00000100263	ENSG00000132471
Uniprot IDs		A0A024R1J2 Q9Y3P4	A0A024R8L1 Q969T9
PDB IDs
Enriched GO Terms of Interacting Partners?
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