SNX33 and DPPA4

Data Source:
BioGRID (two hybrid)

		SNX33	DPPA4
Description		sorting nexin 33	developmental pluripotency associated 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Phosphatidylinositol Binding Identical Protein Binding	Chromatin Binding Protein Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Endosome Organization Endosomal Transport Protein Import Cleavage Furrow Formation Macropinocytosis Negative Regulation Of Endocytosis Positive Regulation Of Membrane Protein Ectodomain Proteolysis Plasma Membrane Tubulation Negative Regulation Of Protein Localization To Cell Surface Positive Regulation Of Protein Localization To Cell Surface	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development
Pathways			POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462)	Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: ADAM15 DPPA4 FASLG FBXO7 NAA10 NAF1 PAK2 ZNF575	35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM
Entrez ID		257364	55211
HPRD ID		11331	16836
Ensembl ID		ENSG00000173548	ENSG00000121570
Uniprot IDs		Q8WV41	Q7L190
PDB IDs		4AKV
Enriched GO Terms of Interacting Partners?
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