CCDC197 and SKA1

		CCDC197	SKA1
Description		coiled-coil domain containing 197	spindle and kinetochore associated complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component		Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process		Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)
Interacting Genes		18 interacting genes: BEX2 C1orf216 CCDC146 CCHCR1 CYTH4 DISC1 FMNL2 KRT3 KRT75 LCA5L NTAQ1 NXF1 RUNX1T1 SKA1 SMARCD1 TXN2 USHBP1 WASHC3	13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1
Entrez ID		256369	220134
HPRD ID		12651	12689
Ensembl ID		ENSG00000175699	ENSG00000154839
Uniprot IDs			A0A024R294 Q96BD8
PDB IDs			4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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