RNF144B and VENTX

Data Source:
BioGRID (two hybrid)

		RNF144B	VENTX
Description		ring finger protein 144B	VENT homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol Integral Component Of Membrane Mitochondrial Membrane	Chromatin Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Senescence-Associated Secretory Phenotype (SASP) Transcriptional Regulation by VENTX
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at voice drop ( 27182965) Caudal middle frontal gyrus volume ( 31530798) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Endometriosis ( 23472165) Facial morphology ( 31763980) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (Dorea) ( 33208821) Pulse pressure ( 30224653) Thiopurine S-methyltransferase activity ( 27770449) Triglyceride levels ( 32203549)
Interacting Genes		28 interacting genes: ANKS1A CDKN1A CHCHD2 CREB5 FOXH1 IL16 OTX1 PAN2 PAX5 PRKAB2 PROP1 PRR35 RIPPLY1 SGTA SGTB TRAF4 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z UBQLN1 USP15 USP2 VENTX ZIC1	93 interacting genes: ABHD11 ADAMTSL4 ARID5A ARSA ATXN7L1 BATF2 BHLHE40 C10orf55 C19orf54 C1orf94 C6orf15 CEACAM6 CERCAM CES1 CFP CREM CSN3 CTAG1A CTAG1B CYSRT1 DAB1 DAZAP2 FAM168B FAM86C1P GLIS2 HOXC8 HYPK INTS11 IRF9 ITIH6 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LITAF LYG1 MAGED1 MIEN1 ODAM PLA2G2F PLEKHB1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RBPMS RHOXF2 RNF144B RNF4 ROR2 RSKR SLC15A2 SMUG1 SOX14 SPRY4 SYNGAP1 TBX15 TBX19 TBX22 TEKT5 TLE2 TMBIM4 TMEM42 TRIP13 TSC1 UBAP2 UBE2I UBQLN2 USP54 VAC14 VHLL WWOX YPEL3 ZBTB32 ZNF34
Entrez ID		255488	27287
HPRD ID		17126	06197
Ensembl ID		ENSG00000137393	ENSG00000151650
Uniprot IDs		Q7Z419	O95231
PDB IDs
Enriched GO Terms of Interacting Partners?
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