ANKK1 and CHN2

Data Source:
BioGRID (two hybrid)

		ANKK1	CHN2
Description		ankyrin repeat and kinase domain containing 1	chimerin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cell Projection	Cytosol Membrane Synapse
	Molecular Function	Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Regulation Of Cell Cycle Process	Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle
Drugs		Fostamatinib
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Experiencing mood swings ( 29500382)	Circulating leptin levels in high cardiovascular risk ( 31766143) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Facial emotion recognition ( 28608620) Facial emotion recognition (angry faces) ( 28608620) Facial emotion recognition (sad faces) ( 28608620) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Loneliness (linear analysis) ( 27629369) Methadone dose in opioid dependence ( 28115739) Obesity-related traits ( 23251661) Psychosis (atypical) ( 24132900) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		6 interacting genes: C12orf57 C2CD6 CHN1 CHN2 HIF1AN YEATS4	14 interacting genes: ANKK1 BAG6 ERBB3 NCK1 NCK2 RAC1 RACGAP1 RANBP3 RB1 SENP8 SHF SMARCD1 TGFBR1 TP53RK
Entrez ID		255239	1124
HPRD ID		10580	04173
Ensembl ID		ENSG00000170209	ENSG00000106069
Uniprot IDs		Q8NFD2	A0A2X0TVW3 B3VCF4 B3VCF5 B3VCF6 B3VCF9 B7Z1V0 B7Z1W9 B7Z215 B7Z232 P52757
PDB IDs			1XA6
Enriched GO Terms of Interacting Partners?
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