SLC41A1 and TRHR

Data Source:
BioGRID (two hybrid)

		SLC41A1	TRHR
Description		solute carrier family 41 member 1	thyrotropin releasing hormone receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Protein-containing Complex	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Magnesium:sodium Antiporter Activity	Thyrotropin-releasing Hormone Receptor Activity Protein Binding
	Biological Process	Cellular Magnesium Ion Homeostasis Magnesium Ion Transport Metal Ion Transport Sodium Ion Transmembrane Transport Cellular Response To Magnesium Ion Magnesium Ion Transmembrane Transport	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways		Metal ion SLC transporters	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Protirelin
Diseases
GWAS		Allergic sensitization ( 30013184) Atrial fibrillation ( 30061737) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Monocyte count ( 27863252) Parkinson's disease ( 19915576 28892059 21738487) Plateletcrit ( 32888494) Prostate cancer ( 25217961) Prostate-specific antigen levels ( 25434496 23269536) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)
Interacting Genes		31 interacting genes: AMIGO1 AQP6 AVPR2 CD79A CLN5 ELOVL7 ERGIC3 FFAR2 FFAR3 GJA5 GJB5 GPR101 GPR152 GPR42 KASH5 LHFPL5 OPRM1 SLC10A1 SLC10A6 SLC13A4 SLC23A2 SSMEM1 SYNDIG1 SYPL2 TAAR9 TBXA2R TLCD4 TMEM237 TMEM248 TMEM31 TRHR	19 interacting genes: ARRB1 C1QL4 COMT EFNA5 FAM241B FXYD6-FXYD2 GJB2 IER3IP1 NIPAL4 PEDS1-UBE2V1 SLC39A2 SLC39A9 SLC41A1 TMEFF2 TMEM218 TMEM239 TRH UBE2J1 YIPF6
Entrez ID		254428	7201
HPRD ID		15388	11767
Ensembl ID		ENSG00000133065	ENSG00000174417
Uniprot IDs		B2RMP2 Q8IVJ1	P34981
PDB IDs
Enriched GO Terms of Interacting Partners?
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