TSGA10IP and FCHSD2

Data Source:
BioGRID (two hybrid)

		TSGA10IP	FCHSD2
Description		testis specific 10 interacting protein	FCH and double SH3 domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Photoreceptor Connecting Cilium Ciliary Basal Body	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	Protein Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Cilium Organization	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Severe influenza A (H1N1) infection ( 26379185) Urate levels ( 31578528)	Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 26663301)
Interacting Genes		112 interacting genes: AKAP8L AMOTL2 AP1B1 ARHGEF9 BHLHB9 BICD2 BICDL2 BIRC7 BRCA1 C1orf109 CALCOCO2 CARD9 CAVIN1 CBY2 CCDC102B CCDC120 CCDC125 CCDC13 CCDC136 CCDC57 CCDC88B CDKN2D CDR2 CDR2L CEP63 CEP70 CIB1 CRACR2B CTAG1A CTAG1B CYSRT1 DMAP1 DYDC1 EFHC1 FCHSD2 FHL3 FRS3 FSD2 GAS8 GOLGA2 GOLGA6A GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF3 JAKMIP1 KANK2 KHDRBS3 KIFC3 KRT24 KRT36 KRT40 KRT86 KRTAP12-2 KRTAP6-2 LCA5L LDOC1 LIPE LMNB2 LMO2 LZTS1 MAGED1 MBD3L1 MDFI MEIS3 MEOX2 MIPOL1 MIS18A MKRN3 MSS51 MTUS2 NAB2 NCOA5 NUTM1 PARVG PDLIM7 PICK1 PRDM6 PRKAR1B PSTPIP1 RASGEF1B RBM4B RBPMS ROPN1 RORB RUNDC3A SAAL1 SORBS3 SPG21 SSX2IP STX11 STX1A TBC1D1 TEKT1 TFIP11 TLE5 TRAF2 TRAF4 TRIM27 TRIM5 TRIM50 TRIP6 TSC1 TTC23 TTC23L UHMK1 WWOX YES1 ZRANB1	52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587
Entrez ID		254187	9873
HPRD ID		08147	13321
Ensembl ID		ENSG00000175513	ENSG00000137478
Uniprot IDs		Q3SY00	O94868
PDB IDs			2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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