MMS22L and DNAJC3

Data Source:
BioGRID (affinity chromatography technology)

		MMS22L	DNAJC3
Description		MMS22 like, DNA repair protein	DnaJ heat shock protein family (Hsp40) member C3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol FACT Complex MCM Complex Nuclear Replication Fork	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Cytosol Membrane Azurophil Granule Lumen Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity Protein Kinase Binding Chaperone Binding Misfolded Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Replication Fork Processing	Negative Regulation Of Protein Kinase Activity Protein Folding In Endoplasmic Reticulum Positive Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Defense Response To Virus Cellular Response To Cold Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Pathways			Viral mRNA Translation XBP1(S) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Automobile speeding propensity ( 30643258) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Chronotype ( 30696823) Gut microbiota (bacterial taxa) ( 27694959) Hand grip strength ( 29691431) Morning person ( 30696823) Multiple sclerosis (OCB status) ( 23785401) Number of sexual partners ( 30643258) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Body mass index ( 28552196)
Interacting Genes		4 interacting genes: ESCO2 FBXW7 RAD51 RPA1	7 interacting genes: DNAJB1 EIF2AK2 EIF2AK3 HSPA1A HSPA5 THAP12 TIRAP
Entrez ID		253714	5611
HPRD ID		12865	03114
Ensembl ID		ENSG00000146263	ENSG00000102580
Uniprot IDs		Q6ZRQ5	A8KA82 Q13217
PDB IDs			2Y4T 2Y4U
Enriched GO Terms of Interacting Partners?
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