ZNF620 and GYS1

Data Source:
BioGRID (two hybrid)

		ZNF620	GYS1
Description		zinc finger protein 620	glycogen synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Glycogen Biosynthetic Process Heart Development
Pathways		Generic Transcription Pathway	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Neuroticism ( 29255261)
Interacting Genes		72 interacting genes: ABLIM3 ATG9A BFSP2 BOLA2 BOLA2B C1orf216 C22orf39 CABP5 CARD9 CCDC102B CCDC6 CCHCR1 CCNC CDCA7L CDKN2D CHAF1A CIB3 CINP CLIC3 CTNNA3 DGCR6L DTX2 EAF1 EEF2KMT EIF4A2 EPM2AIP1 EXOSC5 FHL2 GAS8 GLYCTK GRB2 GYS1 IGFN1 IL16 JRK KCTD9 LMO1 LMO3 MAGOHB MAP2K5 METTL21A MFAP1 MISP MLX MYOZ3 NDOR1 NME7 NOXA1 OAZ3 PIBF1 PIK3R3 PLOD3 POLE2 RIPPLY1 RUSC1 SAAL1 SART3 SLIT1 SNAPC3 TENT5B TPM2 TRAF4 TRIM10 TRIM50 TSEN15 TSR2 USP20 ZBTB16 ZFHX3 ZIC1 ZNF24 ZNF648	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		253639	2997
HPRD ID		15878	00721
Ensembl ID		ENSG00000177842	ENSG00000104812
Uniprot IDs		Q6ZNG0	P13807
PDB IDs
Enriched GO Terms of Interacting Partners?
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