FYB1 and VASP

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		FYB1	VASP
Description		FYN binding protein 1	vasodilator stimulated phosphoprotein
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GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Protein-containing Complex	Cytosol Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding Lipid Binding Protein-containing Complex Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding
	Biological Process	Immune Response Integrin-mediated Signaling Pathway Biological_process T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly Protein Homotetramerization
Pathways		Generation of second messenger molecules Generation of second messenger molecules Signal regulatory protein family interactions	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
Interacting Genes		15 interacting genes: BCAR1 CBL CBLB ENAH EVL FASLG FYN LCP2 NCK2 SH2D1A SKAP1 SKAP2 SRC VASP WAS	44 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP CDC42 CEP43 DMRTB1 DNMBP ENAH ERMAP EVL FAT1 FRS3 FYB1 GSN IQGAP1 LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX
Entrez ID		2533	7408
HPRD ID		04107	03415
Ensembl ID		ENSG00000082074	ENSG00000125753
Uniprot IDs		O15117	A0A024R0V4 P50552
PDB IDs		1RI9 2GTJ 2GTO	1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?
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