VASP and RAPH1

Data Source:
BioGRID (pull down)

		VASP	RAPH1
Description		vasodilator stimulated phosphoprotein	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Exosome	Cytosol Cytoskeleton Plasma Membrane Nuclear Body Lamellipodium Filopodium
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding	Protein Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly Protein Homotetramerization	Signal Transduction
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)	Apolipoprotein B levels ( 32203549) Bone mineral density (total hip) ( 29883787) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Systemic lupus erythematosus ( 28714469)
Interacting Genes		44 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP CDC42 CEP43 DMRTB1 DNMBP ENAH ERMAP EVL FAT1 FRS3 FYB1 GSN IQGAP1 LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	4 interacting genes: CLK1 DNMBP SIAH1 VASP
Entrez ID		7408	65059
HPRD ID		03415	12356
Ensembl ID		ENSG00000125753	ENSG00000173166
Uniprot IDs		A0A024R0V4 P50552	C9K0J5 Q70E73
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW	4GMV 4GN1
Enriched GO Terms of Interacting Partners?
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