FNDC5 and PTS

		FNDC5	PTS
Description		fibronectin type III domain containing 5	6-pyruvoyltetrahydropterin synthase
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GO Annotations	Cellular Component	Extracellular Region Peroxisomal Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Molecular_function Hormone Activity	6-pyruvoyltetrahydropterin Synthase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Biological_process Response To Muscle Activity Positive Regulation Of Brown Fat Cell Differentiation	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development
Pathways			Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs			Mycophenolate mofetil Biopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS			Heel bone mineral density ( 30598549) Objective response to lithium treatment ( 26503763)
Interacting Genes		1 interacting genes: PTS	11 interacting genes: AP2M1 COIL DDIT4L FNDC5 FXR2 LNX1 NTAQ1 PBRM1 PRKG2 SDCBP THAP10
Entrez ID		252995	5805
HPRD ID		17009	11840
Ensembl ID		ENSG00000160097	ENSG00000150787
Uniprot IDs		Q8NAU1	Q03393
PDB IDs		4LSD	3I2B
Enriched GO Terms of Interacting Partners?
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