PTS and COIL

Data Source:
BioGRID (two hybrid)

		PTS	COIL
Description		6-pyruvoyltetrahydropterin synthase	coilin
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body
	Molecular Function	6-pyruvoyltetrahydropterin Synthase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding
	Biological Process	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development	Spliceosomal SnRNP Assembly
Pathways		Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs		Mycophenolate mofetil Biopterin
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Heel bone mineral density ( 30598549) Objective response to lithium treatment ( 26503763)	Height ( 18391951)
Interacting Genes		11 interacting genes: AP2M1 COIL DDIT4L FNDC5 FXR2 LNX1 NTAQ1 PBRM1 PRKG2 SDCBP THAP10	83 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MFAP1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		5805	8161
HPRD ID		11840	02605
Ensembl ID		ENSG00000150787	ENSG00000121058
Uniprot IDs		Q03393	P38432
PDB IDs		3I2B
Enriched GO Terms of Interacting Partners?
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