FUCA2 and TNPO2

Data Source:
BioGRID (two hybrid)

		FUCA2	TNPO2
Description		alpha-L-fucosidase 2	transportin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	Alpha-L-fucosidase Activity Protein Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Entry Of Bacterium Into Host Cell	Protein Import Into Nucleus
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		18 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 PIN1 TNPO2 VWC2 WNT11	52 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C12orf40 C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RAN RBM45 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		2519	30000
HPRD ID		00649	04301
Ensembl ID		ENSG00000001036	ENSG00000105576
Uniprot IDs		Q9BTY2	A0A024R7F7 O14787 Q05D48 Q4LE60
PDB IDs
Enriched GO Terms of Interacting Partners?
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