FSHB and CGA

Data Source:
HPRD (in vitro)

		FSHB	CGA
Description		follicle stimulating hormone subunit beta	glycoprotein hormones, alpha polypeptide
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Follicle-stimulating Hormone Complex	Extracellular Region Extracellular Space Golgi Lumen Follicle-stimulating Hormone Complex
	Molecular Function	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity
	Biological Process	Progesterone Biosynthetic Process Transforming Growth Factor Beta Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Female Gamete Generation Female Pregnancy Positive Regulation Of Cell Population Proliferation Hormone-mediated Signaling Pathway Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Peptide Hormone Processing Positive Regulation Of Cell Migration Follicle-stimulating Hormone Signaling Pathway Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Positive Regulation Of Transcription By RNA Polymerase II Sertoli Cell Proliferation	Regulation Of Transcription By RNA Polymerase II Thyroid Hormone Generation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Peptide Hormone Processing Positive Regulation Of Cell Migration Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Glycoprotein hormones Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events TFAP2 (AP-2) family regulates transcription of growth factors and their receptors ADORA2B mediated anti-inflammatory cytokines production Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases
GWAS		Body mass index ( 25673413) Endometriosis ( 28537267) Endometriosis or migraine ( 32121467) Length of menstrual cycle ( 26732621 30202859) Luteinizing hormone levels in polycystic ovary syndrome ( 26284813) Menarche (age at onset) ( 27182965 25231870) Menopause (age at onset) ( 26414677) Metabolite levels ( 23823483) Number of twin births ( 30760885) Polycystic ovary syndrome ( 26284813 30566500 26416764) Polycystic ovary syndrome (indeterminate subtype) ( 32574161) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Refractive error ( 32231278) Sex hormone levels ( 26014426) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Spontaneous dizygotic twinning ( 27132594) Urate levels ( 31578528) Uterine fibroids ( 31649266)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Atrial fibrillation ( 30061737 29892015) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		3 interacting genes: CGA CGB3 FSHR	9 interacting genes: CGB3 CGB5 FSHB FSHR LHB LHCGR PTN PTPN12 TSHB
Entrez ID		2488	1081
HPRD ID		00644	00342
Ensembl ID		ENSG00000131808	ENSG00000135346
Uniprot IDs		A0A0F7RQE8 P01225	A0A087WYZ4 P01215 Q6I9S8
PDB IDs		1FL7 1XWD 4AY9 4MQW	1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9 4MQW
Enriched GO Terms of Interacting Partners?
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