STH and PRDX6

Data Source:
BioGRID (two hybrid)

		STH	PRDX6
Description		saitohin	peroxiredoxin 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Nucleus Cytoplasm Mitochondrion Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Glutathione Peroxidase Activity Phospholipase A2 Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding 1-acylglycerophosphocholine O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Peroxiredoxin Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Positive Regulation Of MRNA Splicing, Via Spliceosome	Response To Oxidative Stress Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Glycerophospholipid Catabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Oxidant Detoxification
Pathways			Detoxification of Reactive Oxygen Species Neutrophil degranulation
Drugs			2-(N-morpholino)ethanesulfonic acid Copper
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol use disorder (total score) ( 30336701) Brain morphology (MOSTest) ( 32665545) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Idiopathic pulmonary fibrosis ( 24429156) Intracranial volume ( 22504418) Male-pattern baldness ( 28196072) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Parkinson's disease ( 28892059 22438815) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Sleep duration ( 30531941) Subcortical brain region volumes ( 25607358)	Adult body size ( 32376654) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Blood protein levels ( 30072576) Systemic lupus erythematosus ( 26663301) Systemic sclerosis ( 31672989)
Interacting Genes		16 interacting genes: CSTF2 CSTF2T FRS3 MKRN3 NTAQ1 PEF1 PITX1 POGZ PRDX6 SMARCD1 SNRPC SOHLH1 SUOX TFG TLX3 VPS37C	21 interacting genes: CASP10 CASP8 GPX4 GSTP1 HNF4G MAPK1 NCF2 NR4A1 ORM2 PAXIP1 PPARD PSMD8 RARA SFTPA1 STH SUMO2 SUMO4 TERF1 TERF2IP UCHL5 YWHAE
Entrez ID		246744	9588
HPRD ID		06142	03817
Ensembl ID		ENSG00000256762	ENSG00000117592
Uniprot IDs		Q8IWL8	P30041 V9HWC7
PDB IDs			1PRX 5B6M 5B6N
Enriched GO Terms of Interacting Partners?
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