CTAG1A and ARHGEF28

Data Source:
BioGRID (two hybrid)

		CTAG1A	ARHGEF28
Description		cancer/testis antigen 1A	Rho guanine nucleotide exchange factor 28
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GO Annotations	Cellular Component	Cytoplasm	Cytosol Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II TRNA Threonylcarbamoyladenosine Metabolic Process	Cell Morphogenesis Cell Differentiation Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Ephrin Receptor Signaling Pathway Regulation Of Catalytic Activity
Pathways			EPHB-mediated forward signaling
Drugs
Diseases
GWAS			Chin dimples ( 27182965) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) HDL cholesterol ( 30275531) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		76 interacting genes: ACTN3 ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 C1orf109 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1B CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX	6 interacting genes: CTAG1A CTAG1B MAPK8IP1 RHOA YWHAE YWHAH
Entrez ID		246100	64283
HPRD ID		06607	15244
Ensembl ID		ENSG00000268651	ENSG00000214944
Uniprot IDs		P78358	Q8N1W1
PDB IDs		1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB	6BC0 6BC1
Enriched GO Terms of Interacting Partners?
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