AIPL1 and TINF2

Data Source:
BioGRID (two hybrid)

		AIPL1	TINF2
Description		aryl hydrocarbon receptor interacting protein like 1	TERF1 interacting nuclear factor 2
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GO Annotations	Cellular Component	Photoreceptor Inner Segment Nucleus Nucleoplasm Cytoplasm Cytosol	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleoplasm Perinucleolar Chromocenter Nuclear Matrix Nuclear Body Shelterin Complex
	Molecular Function	Farnesylated Protein Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Unfolded Protein Binding	DNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Retina Homeostasis Visual Perception Phototransduction, Visible Light Protein Farnesylation Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Apoptotic Process	Negative Regulation Of Protein ADP-ribosylation Telomere Capping Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Epithelial Cell Proliferation Protein Localization To Chromosome, Telomeric Region Regulation Of Telomere Maintenance Via Telomere Lengthening
Pathways			Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Telomere C-strand synthesis initiation Removal of the Flap Intermediate from the C-strand DNA Damage/Telomere Stress Induced Senescence Inhibition of DNA recombination at telomere
Drugs
Diseases		Leber congenital amaurosis (LCR)	Revesz syndrome; Exudative retinopathy with bone marrow failure
GWAS		C-reactive protein levels ( 29403010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hormone measurements ( 23696881) Manganese levels ( 26025379) Paclitaxel-induced cytotoxicity ( 26015512) Reading disability ( 32108986)	Leukocyte telomere length ( 31171785) Platelet count ( 29403010)
Interacting Genes		10 interacting genes: ACD HSP90AA1 HSPA8 LBX1 NUB1 PLSCR3 POT1 SMAP1 TINF2 TXNL4B	89 interacting genes: ACD ACOT7 ACTB ADA AFAP1L2 AIPL1 AK1 ANKMY2 ANXA4 ANXA5 ANXA8L1 APOBEC3F APPL2 ARHGDIA ARID3B BAG3 BIN2 CALD1 CCDC43 CCDC9 CKB CLK3 CPNE3 CRYGS CTTN DBN1 DCX DHFR2 DPP3 EEF1D EIF4B ENO2 FAM131B FERMT3 FKBP6 GAPDH GNMT HNMT HOXA3 HSP90AB1 IPO5 KCTD17 LASP1 LDHA LGALSL LTA4H MAP2K3 MTNR1B NCDN NOL3 NUDC NUDCD2 OR2H1 PAGE2 PAK1IP1 PEX5 PFKP PGM1 PGM2 PHPT1 PKM PPP1R2 PPP6R3 PRKCB REM2 RGS14 RPSA SARS1 SCRN2 SIAH2 STUB1 SULT1C2 TAGLN TBL1X TERF1 TERF2 TOMM34 TPP1 TRIM15 TRIM16 TRIP10 TUBB TUBB4B TXNDC17 UCHL1 VIPR1 YWHAG ZFP36L1 ZNF790
Entrez ID		23746	26277
HPRD ID		05092	16056
Ensembl ID		ENSG00000129221	ENSG00000092330
Uniprot IDs		F1T0B5 F1T0B6 F1T0C0 F1T0C4 Q7Z3H1 Q9NZN9	Q9BSI4
PDB IDs		5U9A 5U9I 5U9J 5U9K 5V35 6PX0	3BQO 3BU8 5XYF
Enriched GO Terms of Interacting Partners?
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